This tool uses MCL to construct sets of orthologous genes based on sequence similarity search results for all-vs-all genome searches typically using protein sequences. The OrthoMCL site has more information.
- Li L, Stoeckert CJ Jr, and Roos DS. OrthoMCL: identification of ortholog groups for eukaryotic genomes. Genome Res. 2003 Sep;13(9):2178-89. DOI:10.1101/gr.1224503 |
- Chen F, Mackey AJ, Stoeckert CJ Jr, and Roos DS. OrthoMCL-DB: querying a comprehensive multi-species collection of ortholog groups. Nucleic Acids Res. 2006 Jan 1;34(Database issue):D363-8. DOI:10.1093/nar/gkj123 |