UPGMA

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Tree reconstruction method by Sneath & Sokal 1973 [1, 2] using a pairwise distance matrix to construct a root tree -- an Unweighted Pair Group Method with an arithmetic Mean, UPGMA. This bottom-up data clustering method assumes a constant rate of evolution. This is not the case with bacteria, for example, but is recommended for a quick guide to identify similar isolates.

References

  1. Khan HA, Arif IA, Bahkali AH, Al Farhan AH, and Al Homaidan AA. Bayesian, maximum parsimony and UPGMA models for inferring the phylogenies of antelopes using mitochondrial markers. Evol Bioinform Online. 2008 Oct 6;4:263-70. PubMed ID:19204824 | HubMed [Antelopepmid]
  2. [1] OnLine Manual [website]
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